The Foramen Magnum and Neurodegenerative Diseaes.
Foramen magnum in Latin means great hole. It is the largest of several openings called foramen or canals in the base of the skull to allow for the passage of nerves, blood vessels, cerebrospinal fluid and connective tissue into and out of the brain. It is located in the anterior portion (front) of the occipital bone. The picture above shows the skull base looking down into it, the front of the skull is at the top and the foramen magnum is the largest opening and is not labeled.